Horopito,
New Zealand’s
Herbal Hero.
The Horopito Experts.
Forest Herbs Research combines the breakthroughs of modern science together with the wisdom of traditional healing to bring Horopito to the world. Since the 1970’s we have been the driving force behind modern-day use of Horopito.
Horopito (Pseudowintera colorata) is an ancient shrub, over 65 million years old. It is endemic to New Zealand, and it is known as the pepper tree due to the hot peppery taste of the leaves. It is a slow growing plant and prefers the dappled light in the New Zealand rainforest.
Polygodial is the key active in Horopito that is responsible for its health benefits including its antifungal activity.
Pioneering research showed that the polygodial in Horopito was stronger and faster acting than amphotericin B (a common pharmaceutical antifungal)¹. This scientific discovery was a key driver for Forest Herbs Research to continue its own research into this amazing herb and cultivate the only commercial plantation of Horopito globally.
Antimicrobial Properties of Horopito.
Antifungal - Horopito strongly inhibits many species of fungi ²,³, most notably Candida albicans which is often the cause vaginal thrush.
Horopito’s ability to kill Candida has been found to be faster acting and stronger than the pharmaceutical antifungal Amphotericin B and is equal to or better than another pharmaceutical antifungal called Itraconazole.⁴,⁵
Horopito creams, washes and supplements are often used in the treatment of vaginal thrush.
A webinar for practitioners about Horopito as a novel therapy for Candida overgrowth can be viewed using the link below.
Anti-viral - Horopito can kill the virus that causes cold sores (Herpes Simplex Virus-1). In patented research, Forest Herbs Research found that Horopito has exceptional anti-viral properties. Consumer research has found Horopito ointment is an effective cold sore treatment.
Antibacterial - Horopito is an all-rounder when it comes to its anti-microbial powers. In addition to its antifungal and anti-viral properties, polygodial has antibacterial activity against both gram-positive and gram-negative bacteria,⁶ making it an excellent choice as an all-round anti-microbial agent.
Quality Assurance & Polygodial.
It is important to ensure that the Horopito used in the production of natural health products and pharmaceuticals is active in polygodial.
Forest Herbs Research has developed proprietary techniques in its Horopito production to ensure the highest levels of polygodial are retained. Extraction techniques have been carefully developed and focused on maintaining polygodial activity.
Polygodial stability can be easily affected by a number of factors including harvesting, storage, and formulation excipients, therefore careful management of all these factors is required. It is important to note Polygodial is not stable within alcohol solutions.
The Horopito Logo is the gold standard for authentic, premium quality, active Horopito that has been independently tested for polygodial activity.
This logo provides assurance that the Horopito is sustainably sourced from Forest Herbs New Zealand farm and is active in polygodial to deliver effective dosage levels.
References
1. McCallion RF et al. Antibiotic compounds from New Zealand plants, II: polygodial, an anti-candida agent from Pseudowintera colorata. Planta Med 44:134 1982.
2. Lee SH et al. In vitro antifungal susceptibilities of Candida albicans and other fungal pathogens to polygodial, a sesquiterpene dialdehyde. Plant Med. 65:204-8. 1999.
3. Nakajima, J., Papaah, P., Yoshizawa, M., Marotta, F., Nakajima, T., Mihara, S., & Minelli, E. (2007). Effect of a novel phyto-compound on mucosal candidiasis: Further evidence from an ex vivo study. Journal of Digestive Diseases. 8, 48-51.
4. Kumari, A., Bishier, M. P., Naito, Y., Sharma, A., Solimene, U., Jain, S., Yadava, H., Minelli, E., Momella, C., & Marotta, F. (2011). Protective effect of an oral natural phytonutrient in recurrent vulvovaginal candidiasis: a 12-month study. Journal of Biological Regulators and Homeostatic Agents, 25 (4), 543–551.
5. Chopra V., Marotta F., Kumari A., Bishier M.P., He F., Zerbinati N., Agarwal C., Naito Y., Tomella C., Sharma A., Solimene U. (2013) Prophylactic strategies in recurrent vulvovaginal candidiasis: a 2-year study testing a phytonutrient vs itraconazole. Journal of Biological Regulators and Homeostatic Agents, 27(3):875-82.
6. McCallion RF et al. Antibiotic compounds from New Zealand plants, II: polygodial, an anti-candida agent from Pseudowintera colorata. Planta Med 44:134 1982.
7. Kubo, I., Fujita, K., Lee, S. H., & Ha, T. J. (2005). Antibacterial Activity of Polygodial, Phytotherapy Research, 19, 1013-1017